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Pulmonary Cell NewsResearchers demonstrated that selective deletion of stromal androgen-receptor expression in prepubescent Shh responsive Gli1-expressing cells significantly impeded pubertal prostate epithelial growth and development.
[Development]
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Olson, A. W., Le, V., Wang, J., Hiroto, A., Kim, W. K., Lee, D.-H., Aldahl, J., Wu, X., Kim, M., Cunha, G. R., You, S., & Sun, Z. (2021). Stromal androgen and hedgehog signaling regulates stem cell niches in pubertal prostate development. Development, dev.199738. https://doi.org/10.1242/dev.199738 Cite
