Advances of Natural Activators for Nrf2 Signaling Pathway on Cholestatic Liver Injury Protection: A Review

Scientists review the effect of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway on alleviating cholestasis, and summarize recent evidence about natural Nrf2 activators with hepatoprotective effect in various models of cholestatic liver injury, thus providing theoretical reference for the development of anti-cholestatic drug.