Intensive Monitoring of Minimal Residual Disease and Chimerism after Allogeneic Hematopoietic Stem Cell Transplantation for Acute Leukemia in Children

Investigators reported the intensive bone marrow monitoring of minimal residual disease using flow cytometry and nested reverse transcription polymerase chain reaction (PCR) whenever a fusion transcript allowed it and chimerism by PCR at eleven timepoints in the first two years after transplant.