Matrilin3/TGFβ3 Gelatin Microparticles Promote Chondrogenesis, Prevent Hypertrophy, and Induce Paracrine Release in MSC Spheroid for Disc Regeneration

Scientists reported that the incorporation of gelatin microparticles coloaded with transforming growth factor beta 3 and matrilin 3 promoted chondrogenic differentiation of adipose-derived MSC spheroids while preventing hypertrophy and terminal differentiation of cells.