Hematopoietic and Non-Hematopoietic p66Shc Differentially Regulates Stem Cell Traffic and Vascular Response to Ischemia in Diabetes

Researchers examined the hematopoietic versus non-hematopoietic role of p66Shc in regulating hematopoietic stem/progenitor cells traffic and blood flow recovery after ischemia in diabetic mice.