Generation of ‘Designer Erythroblasts’ Lacking One or More Blood Group Systems from CRISPR/Cas9 Gene-Edited Human-Induced Pluripotent Stem Cells

Researchers developed erythroblasts with custom phenotypes using CRISPR/Cas9 gene-editing of a human iPSC parent line for the blood group system genes: RHAG, GYPB and XK.