miR-27b Antagonizes BMP Signaling in Early Differentiation of Human Induced Pluripotent Stem Cells

Researchers used miR-27b-inducible human iPSCs (hiPSCs) to investigate the roles of miR-27b in the undifferentiated and early-differentiated stages. In undifferentiated hiPSCs, miR-27b suppressed the expression of pluripotency markers and cell proliferation.