Fibrinolytic Nanocages Dissolve Clots in the Tumor Microenvironment, Improving the Distribution and Therapeutic Efficacy of Anticancer Drugs

Investigators used thrombolytic nanocages with multivalent clot-targeting peptides and fibrin degradation enzymes, such as microplasmin, to dissolve fibrin in the tumor microenvironment and named them fibrinolytic nanocages.