HOTAIR/Sp1/miR-199a Critically Regulates Cancer Stemness and Malignant Progression of Cutaneous Squamous Cell Carcinoma

The long non-coding RNA, HOX antisense intergenic RNA (HOTAIR), is a well-characterized oncogene in multiple human cancers, but not in cutaneous squamous cell carcinoma (CSCC). In this study, researchers investigated the potential role of HOTAIR in the stemness of CSCC.