The m⁶A “Reader” YTHDF1 Promotes Osteogenesis of Bone Marrow Mesenchymal Stem Cells through Translational Control of ZNF839

To identify the possible role of m6A binding protein YTHDF1 in human bone marrow MSCs osteogenesis in vivo, investigators constructed Ythdf1 knockout mice and showed that depletion of Ythdf1 would result in decreased bone mass in vivo.