Liver Sphingomyelin Synthase 1 Deficiency Causes Steatosis, Steatohepatitis, Fibrosis and Tumorigenesis: An Effect of Glucosylceramide Accumulation

Investigators implicated that glucosylceramide accumulation was one of triggers promoting the development of nonalcoholic fatty liver disease into non-alcoholic steatohepatitis, then, fibrosis and tumorigenesis.