Effects of Menopausal Hormone Therapy-Based on the Role of Estrogens, Progestogens, and Their Metabolites in Proliferation of Breast Cancer Cells

The authors describe the biological effects of estrogen, progesterone, and their metaboliteson the proliferation of breast cancer cells, based on relevant research and clinical trials, to improve our understanding of the biological functions of estrogen and progestogen and safety of menopausal hormone therapy.