Vitexin Inhibits APEX1 to Counteract the Flow-Induced Endothelial Inflammation

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The authors demonstrated that vitexin, a natural flavonoid, could inhibit the activation of apurinic/apyrimidinic endonuclease1 (APEX1) to protect vascular endothelium against the adverse effects of atherogenic stimuli.
[Proceedings of the National Academy of Sciences of the United States of America]
Abstract