Live Attenuated Virus Vaccine Protects against SARS-CoV-2 Variants of Concern B.1.1.7 (Alpha) and B.1.351 (Beta)

Researchers assessed the immunogenicity and protective efficacy of sCPD9 in the Roborovski dwarf hamster, a nontransgenic rodent species that was highly susceptible to SARS-CoV-2 and severe COVID-19–like disease.