The Deubiquitinase OTUD1 Inhibits Colonic Inflammation by Suppressing RIPK1-Mediated NF-κB Signaling

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Investigators showed that loss of ovarian tumor deubiquitinase 1 (OTUD1) in mice contributed to the pathogenesis of dextran sulfate sodium-induced colitis via excessive release of proinflammatory cytokines
[Cellular & Molecular Immunology]
Abstract