Downregulation of SFRP2 Facilitates Cancer Stemness and Radioresistance of Glioma Cells via Activating Wnt/β-Catenin Signaling

Researchers found that secreted frizzled-related protein 2 (SFRP2) was downregulated in radiotherapy-treated glioma patients, and low SFRP2 expression was correlated with advanced tumor stage and poor prognosis.