Nuclear Transport Factor 2 (NTF2) Suppresses WM983B Metastatic Melanoma by Modifying Cell Migration, Metastasis, and Gene Expression

Researchers showed that increasing NTF2 expression in WM983B metastatic melanoma cells reduced cell proliferation and motility while increasing apoptosis. They also demonstrated that increasing NTF2 expression in these cells significantly inhibited metastasis and prolonged survival of mice.