ROS-Mediated Anti-angiogenic Activity of Cerium Oxide Nanoparticles in Melanoma Cells

Investigators established a robust synthesis method for faceted nanoceria with primary particle diameters of 5–6 nm. The nanoceria were not cytotoxic to a human melanoma cell line at doses up to 400 μg/mL and were dose-dependently internalized by the cells.