Targeting a Splicing-Mediated Drug Resistance Mechanism in Prostate Cancer by Inhibiting Transcriptional Regulation by PKCβ1

By
Justin.choi
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0
14
PKCβ inhibition reduced total androgen receptor (AR) gene expression, thus reducing AR-V7 protein levels and sensitizing prostate cancer cells to current anti-androgen therapies.
[Oncogene]

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