DOT1L Activity in Leukemia Cells Requires Interaction with Ubiquitylated H2B That Promotes Productive Nucleosome Binding

By
Justin.choi
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0
8
Aberrant genomic localization of DOT1L was implicated in mixed lineage leukemia-rearranged leukemias, an aggressive subset of leukemias that lacks effective targeted treatments.
[Cell Reports]

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