Pharmacological Perturbation of CXCL1 Signaling Alleviates Neuropathogenesis in a Model of HEVA71 Infection

Investigators showed that Human Enterovirus A71 (HEVA71)-infected astrocytes released CXCL1 which supported viral replication in neurons by activating the CXCR2 receptor-associated ERK1/2 signaling pathway.