Mitochondrial-Derived Damage-Associated Molecular Patterns Amplify Neuroinflammation in Neurodegenerative Diseases

Investigators describe in detail the damage-associated molecular patterns that induce or aggravate neuroinflammation in neurodegenerative diseases including mtDNA, mitochondrial unfolded protein response, mitochondrial reactive oxygen species, adenosine triphosphate, transcription factor A mitochondria, cardiolipin, cytochrome c, mitochondrial Ca2+ and iron.