Fusobacterium nucleatum Reduces METTL3-Mediated m⁶A Modification and Contributes to Colorectal Cancer Metastasis

Researchers uncovered that Fusobacterium nucleatum induced a dramatic decline of m⁶A modifications in CRC cells and patient-derived xenograft tissues by downregulation of an m⁶A methyltransferase METTL3, contributing to inducation of CRC aggressiveness.