A Potent Human Monoclonal Antibody with Pan-Neutralizing Activities Directly Dislocates S Trimer of SARS-CoV-2 through Binding Both Up and Down Forms of RBD

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Scientists demonstrated mAb 35B5 efficiently neutralizes both wild-type (WT) SARS-CoV-2 and variants of concern, including B.1.617.2 variant, in vitro and in vivo.
[Signal Transduction and Targeted Therapy]
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