A Human Barrett’s Esophagus Organoid System Reveals Epithelial-Mesenchymal Plasticity Induced by Acid and Bile Salts

To explore a role for reflux-induced epithelial-mesenchymal plasticity in Barrett’s esophagus, scientists established and characterized human Barrett’s organoids, and sought evidence of epithelial-mesenchymal plasticity after treatment with acidic bile salts