CRABP1-CaMKII-Agrn Regulates the Maintenance of Neuromuscular Junction in Spinal Motor Neuron

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Scientists established a sequenced motor neurons (MN)-muscle co-differentiation system to engineer an in vitro functional 3D NMJ model for molecular studies and demonstrated that Cellular retinoic acid-binding protein 1 (CRABP1) in MNs contributes to NMJ formation and maintenance.
[Cell Death & Differentiation]

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Abstract