CRABP1-CaMKII-Agrn Regulates the Maintenance of Neuromuscular Junction in Spinal Motor Neuron

Scientists established a sequenced motor neurons (MN)-muscle co-differentiation system to engineer an in vitro functional 3D NMJ model for molecular studies and demonstrated that Cellular retinoic acid-binding protein 1 (CRABP1) in MNs contributes to NMJ formation and maintenance.