Human Mesenchymal Stromal/Stem Cells Recruit Resident Pericytes and Induce Blood Vessels Maturation to Repair Experimental Spinal Cord Injury in Rats

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Proteomic analyses of human angiogenesis-related factors produced by human adipose tissue-derived stromal/stem cells (hADSCs) showed that both pro- and anti-angiogenic factors were produced by hADSCs in vitro, but only those related to vessel maturation were detectable in vivo.
[Scientific Reports]
Menezes, K., Rosa, B. G., Freitas, C., da Cruz, A. S., de Siqueira Santos, R., Nascimento, M. A., Alves, D. V. L., Bonamino, M., Rossi, M. I., Borojevic, R., & Coelho-Sampaio, T. (2020). Human mesenchymal stromal/stem cells recruit resident pericytes and induce blood vessels maturation to repair experimental spinal cord injury in rats. Scientific Reports, 10(1), 19604. https://doi.org/10.1038/s41598-020-76290-0 Cite
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