The impact of surface charge on the delivery of 5-ASA loaded PLGA nanoparticles into the lumen of organoids was investigated. Alginate and chitosan were used to coat the nanoparticles and provide negative and positive charges on the particles, respectively.
[Marine Drugs]
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Davoudi, Z., Peroutka-Bigus, N., Bellaire, B., Jergens, A., Wannemuehler, M., & Wang, Q. (2021). Gut Organoid as a New Platform to Study Alginate and Chitosan Mediated PLGA Nanoparticles for Drug Delivery. Marine Drugs, 19(5), 282. https://doi.org/10.3390/md19050282 Cite