Response to Elexacaftor/Tezacaftor/Ivacaftor in Intestinal Organoids Derived from People with Cystic Fibrosis

0
190
The authors utilized an intestinal organoid approach to compare in vitro responses to two CFTR modulator drug combinations and to check potential inter-individual variability in therapeutic response to the triple combination.
[Journal of Cystic Fibrosis]
Furstova, E., Dousova, T., Beranek, J., Libik, M., Fila, L., Modrak, M., Cinek, O., Macek, M., & Drevinek, P. (2021). Response to elexacaftor/tezacaftor/ivacaftor in intestinal organoids derived from people with cystic fibrosis. Journal of Cystic Fibrosis, 0(0). https://doi.org/10.1016/j.jcf.2021.07.006 Cite
Abstract