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Pulmonary Cell NewsScientists reported an organoid model of neural tube extension derived from human human PSC aggregates that had been caudalized with Wnt agonism, enabling them to recapitulate aspects of the morphological and temporal gene expression patterns of neural tube development.
[Development]
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Libby, A. R. G., Joy, D. A., Elder, N. H., Bulger, E. A., Krakora, M. Z., Gaylord, E. A., Mendoza-Camacho, F., Butts, J. C., & McDevitt, T. C. (2021). Axial elongation of caudalized human organoids mimics aspects of neural tube development. Development, 148(12). https://doi.org/10.1242/dev.198275 Cite
