B cells

[Oxidative Medicine and Cellular Longevity] Researchers investigated the role of flagellin in promoting immunotherapy efficacy through modulating oxidative stress in regulatory B cells.

[Trends in Molecular Medicine] The authors discuss how recent investigations have uncovered the key contributions of T follicular helper and B cells and their coordinated actions in driving donor-specific antibody generation and immune progression towards antibody-mediated rejection.

[Aging] Investigators indicated that TEAD2/4 were significantly upregulated in HCC compared with normal tissues. Downregulation of TEAD2 promoted the death of HCC cells through inducing ferroptosis by iron accumulation and subsequent oxidative damage.

[Science Immunology] Scientists characterized tissue-resident memory B cells that were stably maintained in the lungs of mice after pulmonary influenza infection.

[Cancer Immunology Research] Investigators tested the in vitro effect of different NK cell engagers, which triggered either NKp46 or NKp30 together with CD16A, and target either CD19 or CD20 to induce killing of pediatric B cell precursor acute lymphoblastic leukemia.

[Nature Communications] Investigators used a CD19−/− mouse model of antibody-deficiency to demonstrate that a relationship exists between dysbiosis, defects in bile acid homeostasis, and gluten-sensitive enteropathy of the small intestine.