Tag results:
Fos
Cell Therapy News
RNA-Seq of Human T Cells after Hematopoietic Stem Cell Transplantation Identifies Linc00402 as a Regulator of T Cell Alloimmunity
[Science Translational Medicine] Linc00402 was increased in donor T cells from patients who underwent allogeneic cardiac transplantation and in murine T cells.
Prostate Cell News
In Vivo CRISPR Inactivation of Fos Promotes Prostate Cancer Progression by Altering the Associated AP-1 Subunit Jun
[Oncogene] Whereas both JUN and FOS have been implicated in prostate cancer, the authors provided evidence that FOS acts as a tumor suppressor during prostate cancer progression and invasion.
Muscle Cell News
FOS Licenses Early Events in Stem Cell Activation Driving Skeletal Muscle Regeneration
[Cell Reports] Investigators identified a prominent FBJ osteosarcoma oncogene mRNA and protein signature in recently activated satellite cells that was rapidly, heterogeneously, and transiently induced by muscle damage.
Cancer Stem Cell News
GDF15 Promotes Glioma Stem Cell-Like Phenotype via Regulation of ERK1/2–C-Fos–LIF Signaling
[Cell Death Discovery] The authors report that growth differentiation factor 15 (GDF15) promotes the glioma stem cell (GSC)-like phenotype in GSC-like cells through the activation of leukemia inhibitor factor (LIF)–STAT3 signaling.
Extracellular Matrix News
Locally Applied Stem Cell Exosome-Scaffold Attenuates Nerve Injury-Induced Pain in Rats
[Journal of Pain Research] Researchers developed an alginate scaffold with human umbilical cord mesenchymal stem cell exosomes to treat nerve injury-induced pain. In vitro studies of PC12 and HEK293 cells were used to evaluate the neuroprotective and neurotrophic effects of exosomes.
Mesenchymal Cell News
Recurrent FOS Rearrangement in Proliferative Fasciitis/Proliferative Myositis
[Modern Pathology] c-FOS immunohistochemistry was negative in 45 cases of selected mesenchymal tumor types with epithelioid components that may histologically mimic PF/PM, including pleomorphic sarcoma with epithelioid features and epithelioid sarcoma.