The authors report that growth differentiation factor 15 (GDF15) promotes the glioma stem cell (GSC)-like phenotype in GSC-like cells through the activation of leukemia inhibitor factor (LIF)–STAT3 signaling.
[Cell Death Discovery]
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Zhu, S., Yang, N., Guan, Y., Wang, X., Zang, G., Lv, X., Deng, S., Wang, W., Li, T., & Chen, J. (2021). GDF15 promotes glioma stem cell-like phenotype via regulation of ERK1/2–c-Fos–LIF signaling. Cell Death Discovery, 7(1), 1–12. https://doi.org/10.1038/s41420-020-00395-8 Cite