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astrocytes

Buprenorphine Alters Microglia and Astrocytes Acutely Following Diffuse Traumatic Brain Injury

[Scientific Reports] Researchers investigated the acute effects of the opioid analgesic buprenorphine on diffuse neuronal/glial pathology, neuroinflammation, cell damage, and systemic physiology.

Disruption of the Blood−Brain Barrier in 22q11.2 Deletion Syndrome

[Brain] Researchers investigated whether the neuroimmune dysregulation vascular phenotype was intrinsically compromised in the most common genetic risk factor for schizophrenia, the 22q11.2 deletion syndrome.

Patient-Derived Glial Enriched Progenitors Repair Functional Deficits Due to White Matter Stroke and Vascular Dementia in Rodents

[Science Translational Medicine] The authors characterized the cellular properties and in vivo tissue repair activity of glial enriched progenitor cells differentiated from human-induced pluripotent stem cells.

Rescue of Maternal Immune Activation-Induced Behavioral Abnormalities in Adult Mouse Offspring by Pathogen-Activated Maternal Treg Cells

[Nature Neuroscience] Scientists showed that adoptive transfer of regulatory T (Treg) cells largely reversed maternal immune activation-induced phenotypes.

Brain Cells Derived from Alzheimer’s Disease Patients Have Multiple Specific Innate Abnormalities in Energy Metabolism

[Molecular Psychiatry] Researchers report that neural progenitor cells and astrocytes differentiated from late-onset Alzheimer’s disease patient-derived induced pluripotent stem cells exhibited multiple inter-related bioenergetic alterations.

Matrix Stiffness Changes Affect Astrocyte Phenotype in an In Vitro Injury Model

[NPG Asia Materials] Researchers established an in vitro model to assess the responses of astrocytes to matrix stiffness changes that may be related to pathophysiology.

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