Rescue of Maternal Immune Activation-Induced Behavioral Abnormalities in Adult Mouse Offspring by Pathogen-Activated Maternal Treg Cells

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Scientists showed that adoptive transfer of regulatory T (Treg) cells largely reversed maternal immune activation-induced phenotypes.
[Nature Neuroscience]
Xu, Z., Zhang, X., Chang, H., Kong, Y., Ni, Y., Liu, R., Zhang, X., Hu, Y., Yang, Z., Hou, M., Mao, R., Liu, W.-T., Du, Y., Yu, S., Wang, Z., Ji, M., & Zhou, Z. (2021). Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal T reg cells. Nature Neuroscience, 1–13. https://doi.org/10.1038/s41593-021-00837-1 Cite
Abstract