Researchers report that neural progenitor cells and astrocytes differentiated from late-onset Alzheimer’s disease patient-derived induced pluripotent stem cells exhibited multiple inter-related bioenergetic alterations.
[Molecular Psychiatry]
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Ryu, W.-I., Bormann, M. K., Shen, M., Kim, D., Forester, B., Park, Y., So, J., Seo, H., Sonntag, K.-C., & Cohen, B. M. (2021). Brain cells derived from Alzheimer’s disease patients have multiple specific innate abnormalities in energy metabolism. Molecular Psychiatry, 1–13. https://doi.org/10.1038/s41380-021-01068-3 Cite