breast cancer

[Molecular Cancer] Investigators discuss in detail the divergence of early metastases as circulating tumor cells (CTCs) and the involvement of microRNAs (miRNAs) as detectable blood-based diagnostic biomarkers that warrant a timely screening of cancer, serial monitoring of therapeutic response, and the dynamic molecular adaptations induced by miRNAs on CTCs.

[Journal of Pathology] The authors explore the concept of field cancerization focusing on histologically normal peri-tumoral tissues: the authors present how field cancerization presents itself pathologically and molecularly within these tissues and discuss how using peri-tumoral tissues can affect research.

[Journal of Cellular and Molecular Medicine] Scientists found that A549 human lung cancer cells stably expressing vestigial-like family member 3 exhibited spindle-like morphological changes, reduction in the epithelial marker E-cadherin and induction of the mesenchymal marker Snail.

[Cellular Oncology] Scientists investigated signaling cascades of B cell lymphoma 6 (BCL6) in the CSC compartment of triple negative breast cancers, and the mechanisms that govern its activity, mainly through Notch signaling.

[Molecular Cancer] Scientists discuss in detail the divergence of early metastases as circulating tumor cells and the involvement of miRNAs as detectable blood-based diagnostic biomarkers that warrant a timely screening of cancer.

[npj Breast Cancer] Investigators showed that sulforaphane (SFN), including its two isomers of R-SFN and S-SFN, significantly inhibited transforming growth factor-β1-induced migration and invasion in breast cancer cells.