caspase-3

[Histology and Histopathology] Researchers reported that TUG1 expression was induced in mouse heart following myocardial ischemia/reperfusion injury as well as in cardiomyocytes subjected to simulated ischemia/reperfusion in vitro.

[International Journal of Pharmaceutics] The authors confirmed the superior efficacy of linogel in terms of marked improvement in the nucleus and subcellular structures in photomicrographs, through histopathological and ultrastructural analysis, which thus fulfilled all the criteria of dermal application.

[Archiv Der Pharmazie] Investigators explored the mechanisms of action of alsevirone in prostate cancer in vitro and in vivo: CYP17A1 inhibition, cytotoxic, apoptotic, and antitumor effects compared with abiraterone.

[Cell Death Discovery] Researchers performed high-throughput screening and identified that oridonin, an ent-kaurene diterpenoid extracted from the Chinese herb Rabdosia rubescens, inhibited DNMT3A R882 mutant leukemic cells at a low-micromolar concentration.

[Journal of Physiology and Biochemistry] Researchers proved that estrogen had a protective effect on both hepatocyte hypoxia re-oxygen challenge and mouse hepatic ischemia reperfusion model.

[Scientific Reports] 3D airway epithelial tissues allowed to mimic exposure conditions in vitro, generated human-relevant toxicology data, and allowed to elucidate the mode of action of pollutants.