Antiproliferative, Proapoptotic, and Tumor-Suppressing Effects of the Novel Anticancer Agent Alsevirone in Prostate Cancer Cells and Xenografts

Investigators explored the mechanisms of action of alsevirone in prostate cancer in vitro and in vivo: CYP17A1 inhibition, cytotoxic, apoptotic, and antitumor effects compared with abiraterone.