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cell transplantation

Accelerated Embryonic Stem Cell Screening with a Highly Efficient Genotyping Pipeline

[Molecular Biology Reports] Scientists optimized and functionally linked magnetic activated cell sorting technology as well as multiplex droplet digital PCR to their ESC screening process to achieve a greater than 60% assurance that ESC clones were correctly targeted.

Human Skin-Resident Host T Cells Can Persist Long Term after Allogeneic Stem Cell Transplantation and Maintain Recirculation Potential

[Science Immunology] Researchers identified and characterize skin-resident T cells in humans defined by their long-term in situ lodgment.

Azacitidine-Induced Reconstitution of the Bone Marrow T Cell Repertoire Is Associated with Superior Survival in AML Patients

[Blood Cancer Journal] Since hypomethylating agents possessed immunomodulatory functions that constituted part of their anti-tumor effect, the authors set out to analyze the bone marrow immune environment by next-generation sequencing of T cell receptor beta repertoires in 51 AML patients treated within the RAS-AZIC trial.

Efficacy and Safety of Mesenchymal Stem Cells Treatment for Multidrug-Resistant Graft-versus-Host Disease after Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation

[Therapeutic Advances in Hematology] Scientists identified the efficacy and safety of MSCs for multidrug-resistant-graft-versus-host disease after haploidentical donor hematopoietic stem cell transplantation.

Autologous NK Cells as Consolidation Therapy Following Stem Cell Transplantation in Multiple Myeloma

[Cell Reports Medicine] The authors demonstrated the feasibility of infusing multiple doses of ex vivo activated and expanded autologous NK cells in patients with multiple myeloma post-autologous stem cell transplantation.

Mustang Bio Provides an Update on its IND Application for MB-207, a Lentiviral Gene Therapy for Treatment of X-linked Severe Combined Immunodeficiency (“XSCID”) in...

[Mustang Bio, Inc.] Mustang Bio, Inc. announced that the FDA has issued a hold, pending Chemistry, Manufacturing and Controls clearance, on the company’s Investigational New Drug application.

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