dendritic cells

[Journal of Experimental Medicine] Scientists showed that Dcir−/− mice spontaneously developed autoimmune enthesitis and sialadenitis, and also developed metabolic bone abnormalities.

[Immunity] Transcriptional profiling of intra-tumoral dendritic cells (DCs) within regressor tumors revealed an activation state of CD11b+ conventional DCs characterized by expression of interferon-stimulated genes.

[International Immunopharmacology] Scientists examined the efficacy of TY101 as an anti-tumor immune reagent combined with HMGN1and R848.

[Communications Biology] Using B16 mouse melanoma and CT26 colon carcinoma as models of stroma-poor tumors, researchers demonstrated that myeloid/dendritic cells were the main sources of TGFβ1 and TGFβ3.

[Scientific Reports] Scientists used mammary tumors with in situ immunomodulation consisting of intratumoral injections of Flt3L to mobilize conventional type-1 dendritic cells (cDC1s), local irradiation to induce immunogenic tumor cell death, and TLR3/CD40 stimulation to activate cDC1s.

[eLife] Scientists constructed a recombinant protein named NMHC which consist of influenza viral conserved epitopes and a superantigen fragment.