epithelial cells

[Science Signaling] Scientists investigated the antiviral activities of long-chain polyPs against SARS-CoV-2 infection.

[Respiratory Research] The authors investigated the role and mechanisms of enhancer of zeste homolog 2 (EZH2) in pulmonary fibrosis in a murine model of LPS-induced acute respiratory distress syndrome (ARDS) and in ex vivo cultured alveolar macrophages and mouse lung epithelial cell line by using 3-deazaneplanocin and EZH2 the small interfering RNA.

[Nature Reviews Immunology] The full scope of these immune changes remains unclear but is likely to involve multiple components, such as immune cells, the extracellular matrix, endothelial and epithelial cells and a myriad of chemokines and cytokines, including transforming growth factor-β.

[Scientific Reports] In vitro analyses confirmed association between overexpression of miR-17-5p and proliferation, migration and invasion in prostate cancer cell lines.

[Nature Reviews Immunology] The authors discuss the emerging understanding of RT-induced immune effects with particular focus on the lungs and gut and the potential immune crosstalk that occurs between these tissues.

[Molecular Therapy] VBIT-12 treatment of cultured colon cells inhibited the DSS-induced VDAC1 overexpression, oligomerization, and apoptosis.