fibroblasts

[Open Biology] Scientists summarize the current knowledge on fibro-adipogenic progenitors cell characteristics, heterogeneity and the cellular crosstalk during skeletal muscle homeostasis and regeneration.

[Gastroenterology] Researchers to identified the origins and contribution of colorectal cancer-associated fibroblasts associated with poor prognosis.

[Scientific Reports] Scientists describe the establishment of primary cocultures of neoplastic mast cells from canine cutaneous mast cell tumors and cancer-associated fibroblasts.

[Aging] The authors investigated the mechanism underlying the protective effects of galangin against H2O2/UVB-induced damage using in vitro and in vivo models of photodamage.

[Archives of Dermatological Research] In an in vitro model of fibrosis, investigators consistently observed the induction of the c-Rel subunit of NF-κB. Functional abrogation of c-Rel by siRNA resulted in diminished cell contractility of dermal fibroblasts in relaxed, but not in stressed 3D collagen matrices.

[Rheumatology] The authors demonstrated that B19V-infected fibroblasts developed typical senescence features such as enlarged and flat-shaped morphology and senescence-associated beta-galactosidase activity similar to that observed in systemic sclerosis (SSc) skin fibroblasts.