fibroblasts

[Nature Reviews Neuroscience] Scientists describe the current knowledge of the location and identity of CNS perivascular cell types, with a particular focus on CNS fibroblasts, including their origin, subtypes, roles in health and disease, and future areas for study.

[Nature Reviews Cancer] The authors discuss the influence that transforming growth factor-β (TGFβ) exerts on the composition and behaviour of different cell populations present in the tumour immune microenvironment, and the context-dependent functions of this cytokine in suppressing or promoting cancer.

[Theranostics] Lung cancer patient-derived cancer cell and cancer-associated fibroblasts were utilized to mimic the tumor microenvironment and reproduced the stemness properties of cancer stem cells in vitro and developed a high-throughput drug screening platform with phenotypical parameters.

[Cell Reports] Researchers used marker-independent stochastic clonal labeling, combined with quantitative modeling of tumor expansion, to uncover pancreatic ductal adenocarcinoma tissue growth dynamics.

[Nanomedicine] Collagen-enriched transfersomes, glycerosomes and glytransfersomes were specifically tailored by the investigators for skin delivery of oleuropein.

[Molecular Brain] Scientists utilized no known disease/healthy cerebral organoids (COs) as normal function controls. At 3–4 and 6–10 months post-differentiation, COs with mutations showed no evidence of disease-related pathology.