Tag results:
influenza
Immunology of Infectious Disease News
A Recombinant Protein Containing Influenza Viral Conserved Epitopes and Superantigen Induces Broad-Spectrum Protection
[eLife] Scientists constructed a recombinant protein named NMHC which consist of influenza viral conserved epitopes and a superantigen fragment.
Immunology of Infectious Disease News
A Regulatory T Cell Signature Distinguishes the Immune Landscape of COVID-19 Patients from Those with Other Respiratory Infections
[Science Advances] Scientists compared the immune signature from hospitalized SARS-CoV-2āinfected patients to patients hospitalized prepandemic with influenza or respiratory syncytial virus.
Immunology of Infectious Disease News
Recruitment of Dendritic Cell Progenitors to Foci of Influenza A Virus Infection Sustains Immunity
[Science Immunology] The authors showed that effective induction of T cell responses against influenza A virus in mice requires reinforcement of the resident lung conventional dendritic cells (cDC) network by cDC progenitors.
Immunology of Infectious Disease News
Development of Molecular Clamp Stabilized Hemagglutinin Vaccines for Influenza a Viruses
[NPJ Vaccines] Scientists demonstrated that a modular trimerization domain known as the molecular clamp allows the efficient production and purification of conformationally stabilised prefusion hemagglutinin from a diverse range of influenza A subtypes.
Immunology of Infectious Disease News
Impaired HA-Specific T Follicular Helper Cell and Antibody Responses to Influenza Vaccination Are Linked to Inflammation in Humans
[eLife] By studying the breadth of anti-hemagglutinin (HA) IgG, serum cytokines, and B and T cell responses by flow cytometry before and after influenza vaccination, investigators showed that formation of circulating T follicular helper cells was associated with high-titre antibody responses.
Immunology of Infectious Disease News
Innate Immune Responses at the Asymptomatic Stage of Influenza a Viral Infections of Streptococcus pneumoniae Colonized and Non-Colonized Mice
[Scientific Reports] Researchers compared innate immune responses in the lungs of healthy colonized and non-colonized mice after Influenza A virus challenge at the initial asymptomatic stage of infection.