lymphocytes

[Science Advances] Investigators found that triggering receptor expressed on myeloid cells 2 (TREM-2) was induced in T cells in the blood and lungs of patients with COVID-19.

[International Journal For Parasitology] Scientists describe clonal expansion in the variable region of immunoglobulin heavy chains of antigen-specific single B cells collected from humans immunized with Pfs230D1-EPA or Pfs25-EPA conjugate vaccines formulated in Alhydrogel®.

[Journal of Cellular and Molecular Medicine] Researchers developed a 6-gene immune-related risk model to predict the survival of patients with lung adenocarcinoma (LUAD) in The Cancer Genome Atlas cohort based on TP53 status, and the predictive ability was confirmed in two independent cohorts.

[Celularity, Inc. (GlobenewsWire, Inc.)] Celularity Inc. announced the US FDA has cleared its Investigational New Drug application for the use of CYNK-101 in combination with standard chemotherapy, trastuzumab and pembrolizumab in patients with first-line locally advanced unresectable or metastatic HER2/neu positive gastric or gastroesophageal junction adenocarcinoma.

[Proceedings of the National Academy of Sciences of the United States of America] Using Zfp683 reporter mice, scientists showed that correlation of Hobit expression with type 1 innate lymphoid cells was tissue- and context-dependent.

[Immunity] Inhibition of IL-10R signaling altered chromatin accessibility and disrupted cooperativity between the transcription factors NFAT and AP-1, promoting a distinct NFAT-associated program.