B Cell Clonal Expansion and Mutation in the Immunoglobulin Heavy Chain Variable Domain in Response to Pfs230 and Pfs25 Malaria Vaccines

Scientists describe clonal expansion in the variable region of immunoglobulin heavy chains of antigen-specific single B cells collected from humans immunized with Pfs230D1-EPA or Pfs25-EPA conjugate vaccines formulated in Alhydrogel®.