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lymphoid cells
ESC & iPSC News
Alchemab Extends Partnership with Medicines Discovery Catapult to Bolster Collaborative Approach to Tackle Alzheimer’s Disease
[Alchemab Therapeutics] Alchemab Therapeutics, a biotechnology company focused on the discovery and development of naturally-occurring protective antibodies in neurodegeneration and oncology, announced an extension of its collaboration with Medicines Discovery Catapult, a national facility enabling the UK’s community to accelerate innovative drug discovery.
Cancer Stem Cell News
Radiation Therapy Regulates TCF-1 to Maintain CD8+ T Cell Stemness and Promotes Anti-tumor Immunotherapy
[International Immunopharmacology] The authors observed that high-dose radiation remarkably increased the enrichment of stem cell-like CD8+ T cells.
Cell Therapy News
Cardiotoxicity from Chimeric Antigen Receptor-T Cell Therapy for Advanced Malignancies
[European Heart Journal] Scientists discuss the pertinent cardiovascular risks of the growing field of CAR-T cell therapy for today’s cardiologists, including incidence, characteristics, and treatment options, and will conclude with an integrated management algorithm.
Human Immunology News
T Lymphocytes in Parkinson’s Disease
[Journal of Parkinsons Disease] Previous studies have shown that T cells play a key role both in the central nervous system and in the periphery, leading to a profound imbalance in the immune network of Parkinson's Disease patients.
Immunology of Infectious Disease News
β-Catenin Regulates HIV Latency and Modulates HIV Reactivation
[PLoS Pathogens] Researchers showed that the transcriptional co-activator and the central mediator of canonical Wnt signaling, β-catenin, inhibited HIV transcription in CD4+ T cells via TCF-4 LTR binding sites.
Immune Regulation News
Link between the EZH2 Noncanonical Pathway and Microtubule Organization Center Polarization during Early T Lymphopoiesis
[Scientific Reports] Scientists investigated whether the EZH2 noncanonical pathway could be involved in early T cell maturation, which required cell polarization.