mass spectrometry

[Journal of Ethnopharmacology] Scientists reported that Anemarrhenae Rhizoma flavonoids inhibited benign prostatic hyperplasia-related inflammation in vivo and in vitro by targeting arachidonic acid metabolism and interfering with cyclooxygenase (COX) and lipoxygenase (LOX) pathways.

[Gene Therapy] The authors demonstrated the validation and application of a novel peptide immunoaffinity liquid chromatography–tandem mass spectrometry assay.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers found that, in contrast to current convention, “immunodominant” SARS-CoV-2 peptides defined by in silico methods often failed to elicit T cell responses recognizing naturally presented SARS-CoV-2 epitopes.

[Cancer Medicine] The function of CAMSAP3 on the regulation of cellular senescence-associated phenotypes in human non-small cell lung cancer H460 cells were determined in CAMSAP3 deletion (H460/C3ko) cells.

[Communications Biology] The authors showed that PIM1, a serine/threonine kinase over-expressed in prostate cancer, phosphorylation of androgen receptor (AR) and 14-3-3 ζ extensively occupied the same sites on chromatin in an AR-dependent manner.

[Cytotherapy] The authors provided a platform for identifying markers for predicting MSC functional capacity using partial least squares regression modeling that could be used as release criteria and guide future manufacturing strategies for mesenchymal stromal cells and other cell therapies.